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P = 0.7597 OA vs OA + saline)

High patient acceptance For many patients, injections often bring psychological fear and discomfort, while oral medication is more easily accepted

Cytogenotoxicity and protective effect of piperine and capsaicin on meristematic cells of Allium cepa L

MOTS-c modulates the FOXO transcription factors and regulates cellular senescence, the state in which aged or damaged cells stop dividing but refuse to die, instead secreting a cocktail of inflammatory signals known as the senescence-associated secretory phenotype (SASP)

However, combining peptides from different classes (e.g., a GH secretagogue + a GLP-1 agonist + an immune peptide) creates unpredictable interaction potential